The bowl touches the floor, and it’s empty before the sound fades. The tail is thumping, but the eyes have already moved to your hands, your plate, and the pantry door. You’ve just fed a full, measured meal, yet the look says nobody has fed this dog in days.
If you share your life with a Lab, you know this scene well. You might joke that your dog is a bottomless pit, but there’s real science behind that behavior. Understanding it is the first step to keeping your dog lean, active, and comfortable for years. Along with the right routine, quality canine supplements can play a supporting role.
In 2016, researchers identified a gene called POMC (pro-opiomelanocortin) that plays a role in obesity in Labrador Retrievers. A specific mutation, a deletion of 14 DNA base pairs, was linked to higher body weight, more body fat, and stronger food motivation.
The POMC gene helps produce signaling molecules involved in appetite regulation, including beta-MSH and beta-endorphin. In a dog with the mutation, that signal may not land as strongly, so the dog can stay hungry even after a full meal.
This means that your Labrador isn’t simply being greedy or badly behaved. Their brain may simply be wired to keep asking for more.
Yes, a genetic test for the POMC mutation is available, and your veterinarian can explain the process. It’s only recommended for Labrador and Flat-Coated Retrievers. There is no specific treatment for the mutation, but its effects can be managed with careful calorie control and regular exercise.
The goal here is to make every calorie count and keep your Labrador’s body moving. These habits might help you:
Always build the plan with your veterinarian, especially for dogs with a known or suspected POMC mutation.

Let’s be clear here first. No probiotic supplements for dogs can switch off a gene, and Puptides isn’t a treatment or a quick fix. It’s a simple daily habit, one scoop sprinkled on food, designed to support the whole dog. The brand says it was developed with veterinarians, nutrition scientists, and longevity researchers. Its ingredients are chosen for absorption, not hype, with no fillers, artificial flavors, or unnecessary additives.
For a Labrador who needs to stay active, these ingredients are worth a look:
Puptides is made for dogs 12 months and older, so it suits young Labradors building good habits as well as seniors. As with any supplement, results vary and consistency matters, so check with your vet before adding one, especially if your dog takes medication or has health conditions.
You can’t change your dog’s genes, but you can change the routine around them. Measure every meal, turn treats into training, keep those walks and games coming, and check in with your vet along the way. If supplementation is appropriate for your dog, Puptides can be added to the daily routine to provide ingredients intended to support mobility, digestion, and cellular energy. Well-chosen canine supplements can’t replace portion control or exercise, but they can be a simple part of the plan.
The stare at the bowl may never go away. What you can do is help your Labrador stay active, comfortable, and full of life for more years to come.
To give your pet daily support, visit Furever Labs to get Puptides today.
Collagen supplements for dogs provide amino acids used in connective tissues such as cartilage, tendons, ligaments, and skin. For Labradors, maintaining healthy body weight and regular activity remains especially important for reducing unnecessary stress on the joints.
Probiotic supplements for dogs may be useful in certain situations, but Puptides is not marketed as a probiotic formula. It contains pumpkin powder, which provides prebiotic fiber to support normal digestion and gut balance.
You can purchase Puptides directly from the official Furever Labs website at fureverlabs.com. The company currently offers a 30-day satisfaction guarantee on qualifying first orders; check the latest refund policy for full terms and conditions.